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Shocking Photos Show Woman's Horrific Reaction To Ibuprofen That Left Her Oozing Yellow Gunk From Eyes & Scales On Skin

A WOMAN suffered a horrific reaction to ibuprofen after a single dose, breaking out in scales across her skin and oozing yellow gunk from her eyes.

The 45-year-old visited the emergency department with severely swollen face, red eyes oozing discharge, yellow-crusted lips and a rash covering her chest and limbs.

The 45-year-old woman suffered a rare reaction to ibuprofen, causing blisters to erupt across her face and discharge to ooze from her eyes

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The 45-year-old woman suffered a rare reaction to ibuprofen, causing blisters to erupt across her face and discharge to ooze from her eyesCredit: onlinelibrary.Wiley.Com She also suffered a rash with target lesions on her limbs

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She also suffered a rash with target lesions on her limbsCredit: onlinelibrary.Wiley.Com

She'd taken a single 800mg of ibuprofen just four hours earlier, after experiencing flu-like symptoms, according to a report published in the journal Clinical Case Reports.

The woman, from Iraq, was diagnosed with Stevens–Johnson Syndrome (SJS), a severe and potentially life-threatening skin disorder associated with certain medications, including ibuprofen.

The rare condition is caused by the immune system over-reacting to a trigger like a mild infection or medication, leading to blistering and peeling of the skin and surfaces of the eyes, mouth and throat. 

Sometimes called toxic epidermal necrolysis, it needs to be treated immediately in hospital.

Doctors examining the woman observed that she had conjunctivitis and discharge leaking out of her eyes, blisters across her face and a yellowish gunk coating her swollen lips.

A rash resembling targets - with a purple or dark area of skin surrounded by a lighter area - also covered her arms and legs.

Though in "distress", the woman appeared fully conscious and tests to asses her heart health and breathing were "unremarkable".

Doctors also conducted a chest X-ray, blood tests and a skin biopsy - the latter confirmed their suspicions that she was suffering from SJS.

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The 45-year-old was admitted in the hospital's intensive care unit, where she was put on an IV drip and given a seven day course of antibiotics and eye drops.

She also had a tube inserted down her throat to administer fluids and had the lesions around her mouth treated with mouthwashes and topical anaesthetics.

From headaches to period pains – here's which painkillers you should be taking

"After seven days of admission, the patient's condition showed significant improvement, prompting her discharge for regular follow-up with a dermatologist, ophthalmologist, and internist," doctors wrote.

Her facial rash and ulcers decreased significantly in the two months following her admission.

"Continuing follow-up appointments with the specialists was crucial to monitor her progress closely and ensure her ongoing recovery," doctors added.

Ibuprofen is widely used and "generally regarded as safe for pain relief and inflammation", they wrote.

What are the symptoms of Stevens–Johnson Syndrome (SJS)?

STEVENS-Johnson syndrome is a rare condition caused by an 'over-reaction' of the immune system to a mild infection or medicine.

It leads to blistering and peeling of the skin and surfaces of the eyes, mouth and throat.

Common drug triggers include:

  • Epilepsy medicines
  • Antibiotics
  • Anti-inflammatory painkillers like ibuprofen
  • In children, Stevens-Johnson syndrome can sometimes be caused by infections like cold or flu, cold sores and glandular fever.

    Stevens-Johnson syndrome can start with flu-like symptoms, such as a high temperature, sore throat, cough and joint pain.

    A skin rash appears a few days later, starting on the upper body and before quickly spreading to the face, arms, legs and other areas of the body, such as the genitals.

    Affected patches may look like a 'target' with a purple or dark area of skin surrounded by a lighter area.

    Initially, the skin may be discoloured but then blisters develop which burst and leave sore areas.

    The mucous membranes – moist areas of tissue such as the eye, inside of the mouth and throat – are also affected with blisters and ulceration.

    As swallowing can become painful, people can be prone to dehydration.

    If the surface of the eye is affected, this could lead to long term damage if not treated promptly.

    It may take several weeks or months for you to fully recover from Stevens-Johnson syndrome.

    And it can cause serious complications, including:

  • Skin problems like a skin infection, changes in skin colour and scarring
  • Problems with organs, such as the lungs, liver and kidneys
  • Eye problems, such as long-term inflammation or sight problems
  • Problems with the vagina or penis caused by scarring
  • You're more likely to get Stevens-Johnson syndrome if:

  • You've had it before after taking a certain medicine
  • You have a weakened immune system – for example, from having a condition like HIV or AIDS, or treatments like chemotherapy
  • A close family member has had Stevens-Johnson syndrome
  • Sources: NHS, Great Ormond Street Hospital

    Yet the woman's rare case highlights the "potential peril" of a severe reaction like SJS caused by the "seemingly innocuous act of reaching for an over-the-counter pain reliever".

    "SJS is more commonly linked to certain infections and other medications, such as antibiotics and anticonvulsants (epilepsy medicines), yet documented cases associated with ibuprofen use have been reported," doctors went on.

    The case "underscores the importance of vigilance, both on the part of healthcare providers and on the public, in recognising potential adverse reactions", they stated.

    "Healthcare providers should exercise caution when prescribing ibuprofen, particularly in patients with a history of adverse drug reactions," doctors involved in the woman's care advised.

    The women pictured two months after she was admitted to hospital

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    The women pictured two months after she was admitted to hospitalCredit: onlinelibrary.Wiley.Com

    Plymouth Mum's Warning After Son, Ten, Diagnosed With Rare Condition

    A Plymouth mum whose little boy promised her he'd fight after being diagnosed with a rare condition wants to warn other parents of the signs.

    Paula Jones says her "mother's instinct" told her something was wrong when her son Toby's bottom lip turned purple. The ten-year-old was "getting over a cold" on March 21 when she noticed the unusual symptom.

    Paula and her husband Neil began to become increasingly worried when their son "got worse". His face was swollen and he was struggling to breathe. He also had a high temperature.

    Read more:

    The 40-year-old mum-of-three took Toby to the GP and was told to go to Derriford Hospital immediately. There, Toby was diagnosed with rare condition Stevens-Johnson syndrome. The condition "presents itself as a cold or flu" at first, but is serious and needs immediate hospital treatment, according to the NHS.

    Toby was taken to the High Dependency Unit at Derriford and Paula was told Toby was "getting worse". She says she was told that doctors "did not know" if Toby would make it.

    But Toby, who Paula describes as a fighter, "promised" her he'd get through it - and he is now recovering at home after coming out of hospital on April 2.

    Paula said: "The doctor said if he gets worse on the way to Derriford Hospital, we'd need to pull over and call 999. It was at that point I realised how serious it was. I went into parent overdrive.

    "I got to the hospital and within 20 minutes he had several specialists with him. They diagnosed him with Stevens-Johnson syndrome.

    "The scary thing is, it starts off like the flu or a cold. Then the body goes into overdrive, the immune system is attacking the body, but in the wrong way. It's a one in a million condition - statistically. But Toby's is even more rare because it was his own mycoplasma that caused it"

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    Paula now wants to warn other parents to trust their instincts. Paula said: "I'd never heard of the condition Stevens-Johnson syndrome, it's so rare. For Toby, it was his own body causing the skin reaction.

    "We were in the children's assessment unit, he was given oxygen as he was struggling to breathe. He came out in ulcerations, in his throat, mouth - any watery part of the body ulcerates with the condition."

    Paula said the condition can be "caused by medicines" in some patients. But in Toby's case, his reaction was caused by an immune response to his own mycoplasma. Mycoplasma is a genus of bacteria that can cause infections in the body.

    Paula also priased the staff at Derriford Hospital, who were "faultless from beginning to end". She said she can't "thank them enough for their round the clock care" of her son and believes he "wouldn't be here without them".

    Toby, who loves football, is now recovering at home with his family, but his parents want to warn other families about Stevens-Johnson syndrome (Image: Paula Jones)

    She said: "He wanted to get home to watch the Argyle game, he loves football. The hospital consultant said Toby's was the 'most remarkable recovery' from Stevens-Johnson syndrome that he'd ever seen."

    Paula added: "I want to raise awareness for other parents - it is such a rare thing, but if speaking about it helps just one other family, that would be amazing."

    What is Stevens-Johnson syndrome?

    The following information has been taken from the NHS website here

    Stevens-Johnson syndrome is a rare but serious skin reaction that's usually caused by taking certain medicines. It needs to be treated immediately in hospital.

    Severe Stevens-Johnson syndrome is sometimes called toxic epidermal necrolysis.

    Causes of Stevens-Johnson syndrome

    Stevens-Johnson syndrome is often caused by your body reacting to certain medicines, particularly some types of:

  • anti-inflammatory painkillers
  • In children, Stevens-Johnson syndrome can sometimes be caused by infections like cold or flu, cold sores and glandular fever.

    Who is at higher risk
  • You're more likely to get Stevens-Johnson syndrome if:
  • you've had it before after taking a certain medicine – you're more likely to get it again if you take that medicine again or other similar medicines
  • you have a weakened immune system – for example, from having a condition like HIV or AIDS, or treatments like chemotherapy
  • a close family member has had Stevens-Johnson syndrome – sometimes your genes can mean you're at higher risk of getting it
  • Symptoms of Stevens-Johnson syndrome

    Stevens-Johnson syndrome can start with flu-like symptoms, such as a high temperature, sore throat, cough and joint pain. The rash usually starts on the upper body before quickly spreading to the face, arms, legs and other areas of the body, such as the genitals. It's not usually itchy. You can also get blisters and sores:

  • on your lips and in your mouth and throat – this can make swallowing painful
  • in the tube that carries pee out of your body – this can cause pain when peeing
  • on your eyes – this can cause eye pain, pain when looking at bright lights and problems with your sight
  • Call 999 or go to A&E if you or your child:
  • has a circular rash that's darker in the middle and lighter around the outside after having an infection or starting a new medicine
  • has a rash and the skin is itchy, red, swollen, blistered or peeling
  • is wheezing
  • has tightness in the chest or throat
  • is having trouble breathing or talking
  • has a swollen mouth, face, lips, tongue or throat
  • These may be signs of a serious reaction like Stevens-Johnson syndrome and may need immediate treatment in hospital.

  • Mum's Warning After Son, 10, Suffers Unusual Symptoms

    A young boy has been diagnosed with a rare condition after suffering unusual symptoms. Toby's mum Paula Jones wants to warn other parents of the signs. Stevens-Johnson syndrome.

    She says her "mother's instinct" told her something was wrong when his bottom lip turned purple as the ten-year-old was getting over a cold on March 21. Paula began to become increasingly worried when Toby's symptoms got worse. His face was swollen and he was struggling to breathe. He also had a high temperature.

    The 40-year-old mum-of-three took Toby to the GP and was told to go to Derriford Hospital immediately. There, Toby was diagnosed with rare condition Stevens-Johnson syndrome. The condition "presents itself as a cold or flu" at first, but is serious and needs immediate hospital treatment, according to the NHS.

    Toby was taken to the High Dependency Unit at Derriford and Paula was told Toby was "getting worse". She says she was told that doctors "did not know" if Toby would make it.

    Toby, who loves football, is now recovering at home with his family, but his parents want to warn other families about Stevens-Johnson syndrome (Image: Paula Jones)

    "Fighter" Toby promised his mum he'd get through it and he is now recovering at home after coming out of hospital on March 26.

    Paula said: "The doctor said if he gets worse on the way to Derriford Hospital, we'd need to pull over and call 999. It was at that point I realised how serious it was. I went into parent overdrive."

    "I got to the hospital and within 20 minutes he had several specialists with him. They diagnosed him with Stevens-Johnson syndrome."

    "The scary thing is, it starts off like the flu or a cold. Then the body goes into overdrive, the immune system is attacking the body, but in the wrong way. It's a one in a million condition - statistically. But Toby's is even more rare because it was his own mycoplasma that caused it"

    Paula now wants to warn other parents to trust their instincts. Paula said: "I'd never heard of the condition Stevens-Johnson syndrome, it's so rare. For Toby, it was his own body causing the skin reaction."

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    "We were in the children's assessment unit, he was given oxygen as he was struggling to breathe. He came out in ulcerations, in his throat, mouth - any watery part of the body ulcerates with the condition."

    Paula said the condition can be "caused by medicines" in some patients. But in Toby's case, his reaction was caused by an immune response to his own mycoplasma. Mycoplasma is a genus of bacteria that can cause infections in the body.

    Paula also praised the staff at Derriford Hospital, who were "faultless from beginning to end". She said she can't "thank them enough for their round the clock care" of her son and believes he "wouldn't be here without them".

    She said: "He wanted to get home to watch the Argyle game, he loves football. The hospital consultant said Toby's was the 'most remarkable recovery' from Stevens-Johnson syndrome that he'd ever seen."

    Paula added: "I want to raise awareness for other parents - it is such a rare thing, but if speaking about it helps just one other family, that would be amazing."






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