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Mouth Sores: Symptoms, Treatment, And Prevention

Mouth sores may look different depending on the cause, appearing a different color than the surrounding tissue, including white, yellow, red, or purple.

The following images show different types of mouth sores. These images are not intended to provide a diagnosis. If you have unexplained mouth sores or mouth sores that come back or last for a long time, it is best to visit a doctor for a diagnosis and treatment.

Canker sores

Canker sores may look like small oval-shaped ulcers in your mouth that appear white, gray, or yellow. They may be surrounded by a red "halo" of irritation. They may also appear as a painful red area.

Canker sores are also called aphthous stomatitis or aphthous ulcers. They are common and affect about 25% of the general population.

They are usually harmless and heal on their own in a couple of weeks. If you have recurring ulcers, it may be due to other conditions, such as Crohn's disease, celiac disease, vitamin deficiency, or HIV.

Subgroups of canker sores include:

  • Mild: Sores are less than 1 centimeter in diameter and heal within 1 to 2 weeks
  • Major: Sores are deeper and larger — 2 to 3 centimeters in diameter — and can take weeks or months to heal
  • Herpetiform: Sores are smaller — 1 to 2 millimeters in diameter — but occur in clusters of 10 to 100 and can take a few weeks to heal
  • What causes canker sores in your mouth?

    Canker sores are commonly caused by trauma like biting the inside of your cheek, burns, allergies, or sensitivities. They may have other causes as well. However, canker sores are not contagious.

    Certain conditions may make you more prone to them. These can include:

  • exposure to toxins in drinking water
  • emotional or psychological stress
  • smoking or a history of smoking
  • Cold sores

    Cold sores look like fluid-filled blisters that appear near the mouth and lips. They can appear red or darker in color. The affected area may tingle or burn before the sore is visible.

    Cold sores are caused by the herpes simplex type 1 virus (HSV-1). Outbreaks may also be accompanied by mild, flu-like symptoms, such as low fever, body aches, and swollen lymph nodes.

    This virus can be dormant inside of your body. Sores may appear when the virus reactivates and last for 1 to 2 weeks. This can occur when the immune system is weak or during times of stress.

    Outbreaks are more common if you:

  • are under stress
  • are ill or have a weakened immune system
  • have had too much sun exposure
  • have a break in the skin of your mouth
  • The virus that causes cold sores is contagious and can be spread through contact with cold sores. It can be spread through kissing, sharing food, or sharing cosmetics. It is also possible to catch HSV-1 when sores cannot be seen.

    Genital herpes, caused by the herpes simplex type 2 virus (HSV-2), can look similar in appearance to cold sores. Both viruses may be spread through sex without a condom or other barrier methods if you or your partner has an active outbreak.

    Folate deficiency and anemia

    A folate deficiency is caused by not having enough folate, also known as vitamin B9. Folate is an important B vitamin used to make and repair DNA. It's critical to proper development in embryos. Being deficient in folate can also lead to folate deficiency anemia.

    Anemia occurs when your supply of red blood cells is too low. When your red blood cells are reduced, damaged, or impaired, you may have problems transporting enough oxygen throughout your body. It can have an impact on different organ systems in your body.

    Both folate deficiency and anemia can cause mouth sores. While folate deficiency can cause anemia, other types of anemia, like iron deficiency anemia, can cause mouth sores as well. These sores may look like small mouth ulcers or canker sores and be white, gray, yellow, or red in color.

    Folate deficiency may also cause additional symptoms, including:

  • fatigue
  • weakness
  • pale skin
  • tongue swelling
  • gray hair
  • growth delay in children
  • Anemia can also cause additional symptoms that may include:

  • pale, cold skin
  • pale gums
  • dizziness
  • lightheadedness
  • fatigue
  • increased or decreased blood pressure
  • racing or pounding heart
  • shortness of breath or trouble breathing
  • Anemia has many causes and may occur quickly or over a long period of time. Anemia that occurs quickly may be caused by:

  • blood loss from injury
  • surgery
  • endometriosis
  • childbirth
  • heavy menstrual periods
  • gastrointestinal conditions such as ulcers, IBD, and cancer
  • Chronic anemia may be related to autoimmune diseases, inherited genetic conditions, overexposure to lead, and other conditions.

    Gingivostomatitis

    Gingivostomatitis is a common infection of the mouth and gums, often seen in children.

    It produces tender sores on the gums or insides of the cheeks. Like canker sores, they can appear grayish or yellow on the outside and red in the center. Pain can range from mild to severe.

    If you have gingivostomatitis, you may also experience mild, flu-like symptoms. These sores may also lead to drooling and pain with eating. Young children may refuse to eat.

    Ulcers caused by this condition can last about 2 to 3 weeks.

    Gingivostomatitis is often caused by viral infections, such as HSV-1 and coxsackievirus, and bacterial infections, such as Streptococcus. These infections can also be caused by not flossing and brushing teeth regularly.

    Infectious mononucleosis

    Infectious mononucleosis, also known as mono, can occur with a rash. This rash can occur on the skin or inside of your mouth. Flat spots may appear pink or purple.

    Infectious mononucleosis is caused by the Epstein-Barr virus (EBV). It often affects adolescents and young adults in high school and college.

    Symptoms may also include:

  • fever
  • swollen lymph glands
  • sore throat
  • headache
  • fatigue
  • night sweats
  • body aches
  • Symptoms typically last for 2 to 4 weeks but may last weeks longer.

    Oral thrush

    Oral thrush is a yeast infection that develops on the inside of your mouth and on your tongue. It's most common in infants and children, but it may be a sign of a weakened immune system in adults. Having dry mouth or taking medications like antibiotics may increase your risk of developing it.

    It looks like creamy white bumps that appear on the tongue, inner cheeks, gums, or tonsils and can be scraped off.

    Oral thrush is caused by an overgrowth of Candida, a type of yeast that naturally occurs in the body. The CDC says this condition is usually treated with antifungal medications for 7 to 14 days.

    Additional symptoms may include:

  • pain at the site of the bumps
  • cotton-like feeling in the mouth
  • loss of taste
  • pain while swallowing or eating
  • dry, cracked skin at the corners of the mouth
  • Hand, foot, and mouth disease

    Hand, foot, and mouth disease is caused by viruses in the enterovirus family. It's common in children under the age of 5.

    It causes painful red blisters in the mouth and on the tongue and gums. You may also experience flat or raised red spots located on the palms of the hands, soles of the feet, buttocks, or genital area. On darker skin tones, bumps may appear skin-colored or grayish-brown in color.

    Other symptoms may include:

  • fever
  • sore throat
  • feeling unwell
  • skin rash
  • Hand, foot, and mouth disease is contagious but usually not serious. The infection is more contagious during the first week. It usually resolves in 7 to 10 days.

    Leukoplakia

    Oral leukoplakia may look like thick, white patches on your tongue and the lining of your mouth. They may be raised, hard, or have a "hairy" appearance. Leukoplakia is common in people who use tobacco of all kinds.

    Leukoplakia can be harmless and often goes away on its own. However, research suggests 1 to 9% of people with this condition may develop oral cancer. If you think you may have this condition, visit a doctor. They may take a sample of the cells for diagnosis.

    Regular dental appointments may help identify leukoplakia early.

    Oral lichen planus

    Oral lichen planus is a chronic inflammatory disorder that affects the mucous membranes of the gums, lips, cheeks, and tongue.

    It may cause white, lacy, raised patches of tissue in the mouth that can resemble spiderwebs. It may also cause tender, swollen patches that are bright red with ulcers. Open ulcers may bleed and may burn, sting, or hurt when you eat or brush your teeth.

    Lichen planus is not contagious. However, it is a chronic condition that cannot be cured.

    Medication, such as corticosteroids and immune response medications, along with using mild toothpaste, may help manage symptoms.

    Celiac disease

    Celiac disease is an atypical immune system response to gluten that can damage the lining of the small intestine. Damage to the villi — the small hair-like threads in your small intestine — may lead to poor absorption of important dietary nutrients like B vitamins, vitamin D, iron, and calcium.

    Vitamin deficiency can lead to conditions like anemia. This may increase your risk of developing mouth ulcers.

    Symptoms range in severity and may differ between adults and children. They can include:

  • diarrhea
  • weight loss
  • stomach pain
  • anemia
  • joint pain
  • bloating
  • gassiness
  • fatty stools
  • skin rash
  • mouth sores
  • In children, symptoms may include:

  • weight loss
  • growth delay
  • delayed puberty
  • chronic diarrhea or constipation
  • stomach pain
  • yellow or discolored teeth
  • Celiac disease is a chronic condition that has no cure, but you can manage celiac disease through diet and avoiding gluten-containing ingredients such as:

  • wheat
  • barley
  • rye
  • critical (a hybrid of wheat and rye)
  • Mouth cancer

    Mouth cancer, or oral cancer, is a type of cancer that originates in the mouth or oral cavity. This includes:

  • lips
  • cheeks
  • teeth
  • gums
  • front two-thirds of the tongue
  • roof and floor of the mouth
  • Cancer is caused by the growth and spread of abnormal cells.

    Oral cancer may look like ulcers, white patches, or red patches that appear inside the mouth or on the lips and do not heal. Doctors use the terms leukoplakia and erythroplakia to describe these tissue changes inside the mouth.

    Other symptoms of oral cancer may include:

  • weight loss
  • bleeding gums
  • ear pain
  • swollen lymph nodes in the neck
  • If you have unexplained white patches inside your mouth, visit a doctor. They can perform a biopsy to check for cancerous or precancerous cells. Early detection of cancers such as oral cancer can improve your outlook.

    Pemphigus vulgaris

    Pemphigus vulgaris is a rare autoimmune disease. Having an autoimmune disease means that your body's immune system mistakenly attacks healthy tissue in your body. Pemphigus vulgaris affects the skin and mucous membranes of the:

  • mouth
  • throat
  • nose
  • eyes
  • lungs
  • genitals
  • anus
  • It can cause painful, itchy skin blisters that break and bleed easily. Blisters in the mouth and throat may cause pain with swallowing and eating.

    Symptoms of pemphigus vulgaris may also include:

  • blisters that start in the mouth or on skin
  • blisters that may come and go
  • blisters that ooze, crust, or peel
  • Treatment usually involves systemic corticosteroids that usually take effect within 3 months.


    Cold Sore Vs. Canker Sore: Understanding The Difference

    Cold sores are most commonly caused by the herpes simplex virus type 1 (HSV-1). This is a common virus — more than 50 percent of Americans ages 14 to 49 carry it.

    [4] Many people get the virus as a child after being kissed by someone who is infected.

    [5]

    Some infected people never develop a cold sore because the virus can lie dormant in the body for years.

    Certain factors can reawaken the virus and spark a cold sore:

    [5]

  • Exposure to strong sunlight
  • Stress
  • Tiredness
  • A fever or infections
  • Hormonal changes
  • Facial procedures or laser treatment
  • HSV-1 and HSV type 2 (HSV-2) are viruses that can cause cold sores, as well as genital herpes. You can get HSV-2 cold sores if you engage in oral sex with someone who has genital herpes, but this isn't the only way to spread these types of cold sores. A person with HSV-2 cold sores can infect another person through kissing, too.

    [3] Likewise, HSV-2 can also be transmitted from a mother's genital tract to her newborn infant, says Allison Arthur, MD, a board-certified dermatologist at the Sand Lake Dermatology Center in Orlando, Florida.

    Canker sores, on the other hand, aren't caused by the herpes virus. The exact cause of canker sores is unknown. But it's believed that certain factors can increase your risk. Some people get a canker sore after eating citrus fruits or acidic foods, whereas others develop sores because of a nutritional deficiency (in, for example, vitamin B12, folic acid, or iron).

    [2] Certain medications, such as nonsteroidal anti-inflammatory drugs like ibuprofen, can also cause canker sores.

    Other factors that can trigger a canker sore include smoking, stress, and an injury inside the mouth.

    [2] Some autoimmune diseases and a weakened immune system are associated with canker sores as well.

    [1]


    Identifying Mouth Sores From Pictures

    Medically reviewed by Edmund Khoo, DDS

    Mouth sores form in places that include your inner cheeks, gums, tongue, lips, and the bottom or roof of your mouth. They can appear as lesions, bumps, blisters, rashes, or white or colored patches that may be painful.

    Mouth sores are related to a wide range of factors that include infection, dental hygiene, or oral cancer. Other mouth sores like a Behcet ulcer or oral lichen planus are symptoms of chronic diseases. Some mouth sores, like aphthous ulcers (canker sores), can occur without a known cause.

    Determining the type of mouth sore you have can help you decide on the right course of treatment. Some mouth sores heal on their own; other types require special care.

    This article includes pictures of mouth sores and ways to identify the types. It also explains how to treat mouth sores and when to consult your healthcare provider and/or a dentist.

    Types of Mouth Sores

    With so many types of mouth sores, it can be difficult to determine whether a bump or lesion is a serious condition. The following pictures and descriptions provide a basis for identifying some of the most common types of mouth sores. Contact your primary care provider and/or a dentist for a more definitive diagnosis and treatment advice.

    Canker Sore (Aphthous Ulcer)

    A canker sore, also known as an aphthous ulcer or recurrent aphthous stomatitis, can appear on the softer parts of your mouth such as your tongue, lips, soft palate, or cheeks. It typically forms as a small pitted lesion that can be painful. A canker sore is often small and round or oval with a yellow-gray color. It typically forms without a known cause.

    The three main forms of canker sores are:

  • Minor aphthous stomatitis: Less than 1 centimeter in diameter

  • Major aphthous stomatitis: Over 1 centimeter in diameter

  • Herpetiform aphthous stomatitis: Pinhead-sized ulcers (smaller than 1 millimeter each) that can merge to form larger ulcers

  • Oral Lichen Planus

    Reproduced with permission from © DermNet and © Raimo Suhonen dermnetnz.Org 2023

    Oral lichen planus is an autoimmune disease that causes chronic inflammation in your mouth. It is characterized by networks of painful white ulcers with fine white lines on your tongue, gums, or inner cheeks. These mouth sores, which can look like a rash in your mouth, can become more painful when you have anxiety or stress.

    Behcet's Ulcer

    Reproduced with permission from © DermNet and © Raimo Suhonen dermnetnz.Org 2023

    A Behcet's ulcer is a painful canker sore that appears on the mucous membranes of your mouth. It is a symptom of Behcet's disease, an autoimmune disorder. This type of mouth sore is round or oval with reddish borders. The lesion can be shallow or deep, appearing alone or in a cluster of multiple lesions.

    Infectious Sores (Herpes)

    Reproduced with permission from © DermNet and © Dr. Mashihul Hossainwww.Dermnetnz.Org 2023.

    Infectious sores (herpes) often look like a cluster of small, fast-developing blisters. They are infectious and spread by skin-to-skin contact with someone who carries the herpes simplex virus (HSV).

    The most common symptoms of infectious sores include the following:

  • Initial redness, heat, swelling, and pain in the affected area before the sores erupt

  • Painful sores that exist under your nose or on your lips

  • Blisters that merge then break open when they seep fluid and crust over

  • Healing in about four to six days

  • Dental Hygiene-Related

    Poor dental hygiene can leave your mouth vulnerable to viral and bacterial infections. These germs can cause gingivostomatitis, a gum and mouth infection that leads to small, painful blister-like sores, gum swelling, and bleeding. Halitosis is also common.

    Recurrent Erythema Multiforme

    Reproduced with permission from © DermNet and © Te Whatu Ora Waikato dermnetnz.Org 2023

    Recurrent erythema multiforme is a bull's-eye lesion. It appears as a round sore with three concentric color zones: a darker center with a blister, a middle raised paler pink circle around the center, and a bright red outermost ring. It typically occurs after a herpes simplex virus (HSV) infection.

    Hand, Foot, and Mouth Disease

    DermNet / CC BY-NC-ND​ Hand foot and mouth disease

    Mouth sores caused by hand, foot, and mouth disease start as small red sores on your tongue and inside your mouth. The spots typically blister and become painful. At the same time, a fever and skin rash on the palms of your hands and soles of your feet may also appear.

    COVID-19-Related Sores

    Oral symptoms have been linked to infection with the SARS-CoV-2 virus causing COVID-19. These include nonspecific mouth ulcers (can be from many causes), which may be accompanied by tongue inflammation and discoloration. However, it is unclear whether these problems are directly related to the virus, underlying conditions, or treatments.

    HIV-Related Sores

    Reproduced with permission from © DermNet and © Dr Richard Ashton dermnetnz.Org 2023

    The human immunodeficiency virus (HIV), the virus that causes AIDS, can cause canker sores on the inside of your cheeks and lips. They may also include red sores on the roof of your mouth and outside of your lips. White or yellowish patches and warts can also occur.

    Leukoplakia

    Reproduced with permission from © DermNet and © Professor Deborah Greenspan dermnetnz.Org 2023

    Leukoplakia causes thickened white patches on the mucous membranes of your mouth. The patches are slightly raised and with a hard surface that can't be scraped away. Leukoplakia patches are usually white or gray and do not cause pain. They are common in smokers.

    Thrush (Oral Candidiasis)

    Reproduced with permission from ©DermNet NZ www.Dermnetnz.Org 2022

    Thrush (oral candidiasis) is an oral yeast infection that causes white or red raised patches inside your mouth or at the back of your throat. It can produce a white coating in your mouth that resembles cottage cheese. Thrush may also involve oral redness and burning.

    Syphilis-Related Sores

    Reproduced with permission from ©DermNet NZ www.Dermnetnz.Org 2022

    Syphilis is a bacterial infection that starts with mouth sores known as chancres during its early stages. These typically appear on your lips or gums. They can also develop at the tip of your tongue or the back of your mouth. Chancres start as red patches that increase into larger open sores that are painful and change in color to red, gray, or yellow.

    Vaping and Smoking-Related Sores

    The nicotine involved in vaping and smoking restricts blood flow to your gums and mucous membranes. These types of mouth sores include abrasions, gingivitis (gum disease), leukoplakia, erosion of the palate, and squamous cell carcinoma (flat, reddish, or brownish patches in your skin).

    Sexually-Transmitted vs. Nonsexually Transmitted Mouth Sores

    Sexually transmitted infections, such as herpes, syphilis, and HIV, are typically spread to the mouth through oral sex. Nonsexually transmitted mouth sores are spread by close physical, nonsexual contact with an infected person. This is typically the course of transmission with infections such as hand-foot-and-mouth disease and COVID-19.

    Cancerous Mouth Sores

    Cancerous mouth sores often have many of the same characteristics as non-cancerous types. It is impossible to identify cancerous mouth sores without a biopsy (removing a sample tissue for analysis in a lab). Contact a healthcare provider if you notice signs of cancerous mouth sores or mouth sores that do not improve within two weeks of eruption.

    Squamous Cell Carcinoma

    Reproduced with permission from © DermNet dermnetnz.Org 2023

    Squamous cell carcinoma in your mouth starts as flat, thin cells that line your mouth and throat. Early signs of this type of oral cancer appear as a sore, lump, or thickening on your lips or inside your mouth. The sore may look like a white or red patch on your gums, tongue, or the lining of your mouth.

    Lymphoma

    Lymphoma is classified as Hodgkin's lymphoma and non-Hodgkin's lymphoma. While it primarily affects your lymph nodes, lymphoma can appear as an infection in your mouth, causing mouth sores on your tonsils and tongue and bleeding gums.

    Mucosal Melanoma

    Mucosal melanoma can affect the mucous membranes in your mouth. Mouth sores can include bleeding lumps, discolored lesions, and ulcers (open sores).

    Learn More: What Is Oral Cancer?

    Home Remedies for Mouth Sores

    Treatment isn't usually necessary for most mouth sores unless the symptoms are unbearable. Most mouth sores will clear on their own within about two weeks, but if they do not, you should see your oral healthcare provider.

    Depending on the cause of your mouth sore, you may be able to use home remedies to treat the problem naturally. There is evidence that the following treatments may help some types of mouth sores, but before starting home remedies, please check with your oral healthcare provider. Home remedies include:

  • Saltwater solution: Rinsing your mouth with a saltwater solution (1 teaspoon of table salt and 8 ounces of lukewarm water) promotes healthy gums and promotes healing. The mixture can dry out canker sores, kill bacteria, and reduce acidity that can irritate your mouth tissue.

  • Baking soda solution: A baking soda solution (one-half teaspoon of baking soda with 1 cup of water) can be used as a rinse to neutralize the oral pH and increase salivary output, which promotes healing.

  • Honey: Honey has healing effects that include antibiotic properties when used as a topical treatment for recurrent canker sores.

  • Coconut oil: Coconut oil has antimicrobial properties due to its high level of lauric acid ( a natural antibacterial agent). It may help treat mouth sores by reducing oral bacterial levels related to a mouth infection and reducing pain. Apply coconut oil directly onto the sore.

  • Hydrogen peroxide solution: Hydrogen peroxide can kill bacteria, which can promote healing. Use a cotton swab to apply a mixture of equal parts hydrogen peroxide and water to a mouth sore. Follow this with a dab of Milk of Magnesia (magnesium hydroxide) to the sore.

  • Clove oil: Clove oil has natural antibacterial and anti-inflammatory agents to promote healing. It also has therapeutic actions to reduce oral pain caused by mouth sores.

  • Alum powder: Alum powder, made from potassium aluminum sulfate, has astringent properties that may help dry out canker sores. Apply a paste (made of a small amount of alum powder and a drop of water) onto the sore. Rinse thoroughly after one minute.

  • Learn More: How to Get Rid of Canker Sores

    Over-the-Counter Mouth Sore Treatments

    Some mouth sores may improve with the use of over-the-counter (OTC) treatments. For best results, follow the manufacturer's instructions and only use products intended for your mouth. You can find the following options in grocery stores, pharmacies, and online retailers:

  • Local anesthetics: Topical gels or creams that contain lidocaine or benzocaine can relieve the pain when these oral products are applied directly to the surface of a mouth sore.

  • Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs may help relieve the pain and inflammation of mouth sores while they heal.

  • Mouthwashes with chlorhexidine or triclosan: These ingredients can help prevent the growth of germs that could delay healing or aggravate inflammation.

  • Mouth sores caused by infections or other medical conditions typically require stronger treatments, such as antibiotics, to eradicate the germs. When underlying conditions exist, treatment involves managing those symptoms and treating the mouth sores.

    Learn More: Types of Mouth Infections and How to Treat Them

    When to See a Healthcare Provider

    While some types of mouth sores are minor and can quickly resolve on their own, contact a healthcare provider if any of the following characteristics apply to your condition:

  • You notice the mouth sore soon after starting a new medication or other type of medical treatment.

  • Large white patches form on the roof of your mouth or your tongue, indicating a possible infection.

  • The mouth sore does not improve within two weeks of eruption.

  • You have a weakened immune system from conditions such as HIV, cancer, or other diseases.

  • You have a fever, skin rash, drooling, or difficulty swallowing.

  • You have a personal history of alcohol use, smoking, or using smokeless tobacco.

  • You have had treatment involving chemotherapy, radiation therapy, a bone marrow transplant, or stem cell therapy.

  • Learn More: Recurrent Mouth Ulcers and Canker Sores in Children

    Summary

    It's difficult to known when a mouth sore indicates a mild or more serious problem. Many types of mouth sores have features that can look alike when viewed in the darkness of your mouth. Other factors like medications and your diet can impact the way a mouth sore looks in your mouth versus the norm.

    No matter its cause, a painful mouth sore can affect how you eat and speak. Some can even change the way you look, adding to the stress and anxiety.

    If you are unsure about the cause of a mouth sore or have a mouth sore that hasn't changed in two weeks, contact your primary care provider and/or your dentist. Getting the correct diagnosis as early as possible can help you get the best results when treating any mouth sore.

    Read the original article on Verywell Health.

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